Antengene’s Eltanexor (ATG-016) Receive the NMPA’s IND Approval for P-II Study to Treat Patients with High-Risk Myelodysplastic Syndromes
- The NMPA has approved a P-II open-label study to evaluate the safety, tolerability & efficacy of SINE compound (ATG-016) in patients with high-risk MDS
- The ongoing P-I/II (KCP-8602-801) trial evaluated the safety, tolerability, and efficacy of ATG-016 in patients of 6 sub-parts of r/r cancer indications initiated by Karyopharm
- The company will take part in the Part F P-II (KCP-8602-801) study for high-risk MDS patients while the Part F P-I study showed an ORR of 53% and m-OS of 9.86mos. in efficacy-evaluable patients. ATG-016 has received ODD from the US FDA for MDS & is currently evaluating in the (HATCH) study, P-I/II (REACH) registration-track study & P-I/II for advanced solid tumors
Ref: PR Newswire | Image: Antengene
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