Bio-Thera Solutions Reports First Patient Dosing of BAT8007 in P-I Clinical Study for the Treatment of Advanced Solid Tumors
- The first patient has been dosed in the P-I clinical study evaluating the safety and tolerability of BAT8007, an antibody-drug conjugate targeting Nectin-4 in patients with advanced solid tumors
- The purpose of the study is to determine the MTD, and RP2D, and to evaluate the PK and preliminary efficacy in patients with advanced solid tumors
- BAT8007 is an ADC targeting Nectin-4 that has been developed using Bio-Thera’s ADC linker-payload incl. a cleavable but systemically stable linker, a small molecule topoisomerase I inhibitor & high DAR. In both in vitro and in vivo pharmacological studies, BAT8007 demonstrated strong anti-tumor activity, good stability, and safety
Ref: Bio-Thera Solutions | Image: Bio-Thera Solutions
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