UCB Published P-III Studies (BE MOBILE 1 & 2) Results of Bimekizumab for Axial Spondyloarthritis in the Annals of the Rheumatic Diseases
- The 24wk. results from the P-III studies (BE MOBILE 1 & 2) evaluating the efficacy & safety of bimekizumab vs PBO in adult patients with axSpA incl. active nr-axSpA & AS
- Both trials met their 1EPs & 2EPs @16wk., the therapy showed an improvement in the nr-axSpA & AS and patients continued to increase to 24wk. who achieved ASAS40 response treated with bimekizumab at baseline. Additionally, the ASAS40 responses in patients who switched from PBO to bimekizumab @16wk. reached comparable levels @24wk. as those seen in bimekizumab-randomized patients
- The safety profile was consistent with prior reported studies with no new safety signals. Bimekizumab is a humanized monoclonal IgG1 Ab inhibiting interleukin 17A & interleukin 17F
Ref: UCB | Image: UCB
Related News:- UCB Publishes P-III (BE OPTIMA) and (BE COMPLETE) Studies Results of Bimekizumab for Psoriatic Arthritis in The Lancet
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