OncoSec Reports Result of Keytruda + TAVO in P-II KEYNOTE-890 Study for Refractory Metastatic Triple Negative Breast Cancer
Shots:
- The P-II KEYNOTE-890 study results involve assessing of Keytruda (200mg- IV) + TAVO (tavokinogene telseplasmid) in 25 patients with heavily pretreated- CT/radiotherapy refractory mTNBC who failed an average of 3.5 prior lines of CT
- The P-II KEYNOTE-890 study result: @3mos. 20% + tumor reduction; two patients showed 66% tumor reduction including reduction of liver lesions; well tolerated
- OncoSec’s TAVO (tavokinogene telseplasmid) is an immunotherapy platform- allowing the intratumoral delivery of IL-12 and Keytruda (pembrolizumab) is mAb targeting PD-1- blocking the interaction b/w PD-1 and its ligands- PD-L1 and PD-L2 thus activating T-lymphocytes affecting both tumor & healthy cells
Ref: OncoSec | Image: OncoSec Medical Incorporated (ONCS)
Click here to read the full press release
This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com