Regeneron Presents P-III Trial Results of Dupixent (dupilumab) for Atopic Hand and Foot Dermatitis at AAD 2023
Shots:
- The P-III trial evaluating Dupixent (200/300mg, q2w) in 133 adolescents & adults with mod. to sev. atopic hand & foot dermatitis
- The trial met its 1EPs & 2EPs i.e., patients achieved clear or almost clear skin on hands & feet (40% vs 17%), 52% vs 14% reduction in itch on hands & feet, 69% vs 31% avg. reduction in signs of hand & foot lesions from baseline, 75% vs 40% improvement in hand eczema disease severity from baseline along with significant improvements in measures of hand and foot skin pain, sleep, and hand eczema-related QoL
- The safety results were similar to the known safety profile of Dupixent, overall rates of AEs (66% vs 74%), patients used one rescue medication (3% vs 21%)
Ref: GlobeNewswire | Image: Regeneron
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