Microbiotica Entered into a Clinical Trial Collaboration Agreement with MSD to Evaluate MB097 + Keytruda (pembrolizumab) for Melanoma
Shots:
- The companies collaborated to conduct the P-I trial evaluating the safety tolerability & initial signs of clinical activity of MB097 + Keytruda in patients with melanoma
- Microbiotica will be the study sponsor & MSD will be responsible to supply Keytruda. MB097 is an orally administered live biotherapeutic product consisting of a defined consortium of 9 bacterial strains. The goal of MB097 is to increase the effectiveness of ICIs
- In in vivo tumor models, MB097 showed strong anti-tumor efficacy when combined with ICIs. It also showed multiple immuno-stimulatory mechanisms in primary human immune cell assays, incl. activation of cytotoxic T lymphocytes & in vitro tumor cell eradication
Ref: Businesswire | Image: Microbiotica
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