Mustang Bio Presents Updated P-I/II Trial Results of MB-106 for the Treatment of Waldenstrom Macroglobulinemia at EHA 2023
- The updated results from an ongoing P-I/II trial evaluating MB-106 in patients with WM. The therapy is being developed in collaboration b/w Mustang & Fred Hutchinson Cancer Center to treat patients with r/r B-NHLs & CLL
- The results showed that 83% responded to treatment, incl. CR (2), VGPR (1), PR (1) & minor response (1), 1 patient experienced SD, patients remained in remission who achieved a CR for 22mos., IgM level decreased rapidly to the normal range, no patient has started additional anti-WM treatment after being treated with MB-106
- CRS were reported in 5 patients: 2 with grade 1, 3 with grade 2 while 1 experienced grade 1 ICANS & no grade 3 or 4 CRS or grade 2, 3, or 4 ICANS were seen. The therapy continues to demonstrate favorable safety & efficacy profile
Ref: GlobeNewswire | Image: Mustang Bio
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