Janssen Signs an Exclusive Worldwide License and Option Agreement with Genmab for its HexaBody-CD38

Janssen Signs an Exclusive Worldwide License and Option Agreement with Genmab for its HexaBody-CD38

Shots:

  • Genmab to receive $150M as option exercise fee, $125M as development milestones and 20% royalties on sales of HexaBody-CD38 till 2031, following 13-20% in future. Genmab to fund the R&D activities till completion of clinical proof of concept studies in multiple myeloma and diffuse large B-cell lymphoma
  • Janssen to get exclusive WW license option to develop & commercialize HexaBody-CD38, based on the proof of concept study results. If the option is not exercised, Genmab will get rights to develop and commercialize HexaBody-CD38 for DARZALEX-resistant patients and other indications (Ex- multiple myeloma or amyloidosis indications)
  • HexaBody-CD38 is a next-generation CD38 mAb product developed using Genmab’s HexaBody technology and has shown promising pre-clinical data in multiple myeloma, lymphoma and leukemia models  

Click here to read full press release/ article | Ref: Janssen | Image: World Myeloma Forum