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Janssen Reports Results of Ponesimod in P-III OPTIMUM Study for Relapsing Multiple Sclerosis

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Janssen Reports Results of Ponesimod in P-III OPTIMUM Study for Relapsing Multiple Sclerosis

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  • The P-III OPTIMUM study involves assessing of Ponesimod (20 mg) vs Aubagio (teriflunomide- 14mg) in 1-133 patients with relapsing multiple sclerosis for 108 weeks
  • The study resulted in meeting 1 EPs of annualized relapse rate (ARR) up to the end of the study and most of its 2 EPs with no new observed signals
  • Ponesimod is a selective sphingosine-1-phosphate receptor 1 (S1P1) modulator- inhibiting S1P activity and reduces the number of circulating lymphocytes with its anticipated EMA’s approval for relapsing MS in H2’19

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Ref: Janssen | Image: Janssen 


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