BioLineRx Reports Results of BL-8040 in Combination with Keytruda (pembrolizumab) in P-IIb Trial for Patients with Metastatic Pancreatic Cancer

BioLineRx Reports Engraftment Data of BL-8040 in P-III GENESIS Trial for Patients with Multiple Myeloma

Shots:

  • The P-IIa study involves assessing of BL-8040 + Keytruda in 20 patients with metastatic pancreatic cancer who progressed after at least one prior line of chemotherapy
  • The overall median time to progression was 2 mos. , while the median time to progression for patients showing disease control was 7 mos. and mOS was 7 mos. , while median survival for the patients showing disease control was 12 mos., was well-tolerated results plus showed 20% disease control rate
  • BL-8040 is a short synthetic peptide acting as an antagonist for a chemokine receptor CXCR4 and is also being evaluated in P-IIa COMBAT/KEYNOTE-202 study in combination with Keytruda and CT for patients with metastatic pancreatic cancer patients. BioLineRx in-licensed BL-8040 from Biokine Therapeutics

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