Inotrem Signs a Worldwide License agreement with Roche Diagnostic for CDx Test in Septic Shock

Inotrem, Signs, Worldwide, License Agreement, Roche Diagnostic, CDx Test, Septic Shock


  • Inotrem enters into a global licensing agreement with Roche Diagnostics to commercialize mechanism-based CDx test utilizing a soluble plasma protein (sTREM-1)
  • The collaboration leads towards the enhancement of Inotrem’s approach targeting TREM-1 pathway and allows it to focus on the development of a nangibotide-based septic shock treatment
  • LR12 (nangibotide) is the first-in-class TREM-1 inhibitor with the potential to treat septic shock and MI. Inotrem has initiated its P-IIb ASTONISH study with a focus to demonstrate the efficacy of nangibotide, and bring clinically relevant proof of clinical activity in patients with septic shock

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