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IDEAYA and Pfizer Collaborate to Evaluate IDE196 + Binimetinib in Solid Tumors Harboring GNAQ or GNA11 Hotspot Mutations

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IDEAYA and Pfizer Collaborate to Evaluate IDE196 + Binimetinib in Solid Tumors Harboring GNAQ or GNA11 Hotspot Mutations

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  • The companies entered into a clinical trial collaboration and supply agreement to evaluate the combination of IDE196 + binimetinib for GNAQ or GNA11 hotspot mutated solid tumors- including MUM- CM & CRC. The study is expected to be initiated in mid-2020
  • The clinical study will assess whether inhibition of the MAP-Kinase pathway at two nodes will enhance the response rate- depth and durability of clinical benefit. The companies will form a JDC and shares result of clinical study
  • IDEAYA will sponsor the study while Pfizer will provide its binimetinib for the study. IDE196 is a PKC inhibitor and binimetinib is a MEK inhibitor for which Pfizer has exclusive rights in the US and Canada

Click here ­to­ read full press release/ article | Ref: PRNewswire | Image: IDEAYA


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