Logo

AstraZeneca and Daiichi Sankyo Provide Updates of Enhertu (fam-trastuzumab deruxtecan-nxki) in HER2-Positive Metastatic Colorectal Cancer and HER2-Mutant Non-Small Cell Lung Cancer #ASCO20

Share this

AstraZeneca and Daiichi Sankyo Provide Updates of Enhertu (fam-trastuzumab deruxtecan-nxki) in HER2-Positive Metastatic Colorectal Cancer and HER2-Mutant Non-Small Cell Lung Cancer #ASCO20

Shots:

  • The two companies divulged the results of ongoing P-II DESTINY-CRC01 study assessing Enhertu in patients with HER2+ unresectable and/or m-colorectal cancer- prior treated with 2L standard therapies. Results: ORR (45.3%); DCR (83.0%); PFS (6.9mos.); subgroup patients including patients with treated with a prior anti-HER2 regimen- ORR (43.8%) with a median treatment duration of 4.8mos.
  • The ongoing P-II DESTINY-Lung01 study demonstrated that ENHERTU achieved tumor response in patients with HER2m unresectable/ mNSCLC progressed with one or more systemic therapies. Results: ORR (61.9%); DCR (90.5%); PFS (14.0 mos.)
  • Both the results were presented at ASCO20. ENHERTU is a HER2-directed Ab and topoisomerase inhibitor conjugate indicated to treat patients with unresectable/ m-HER2+ breast cancer who have received 2+ prior anti-HER2-based regimens in the metastatic setting

Click here- Click here to­ read full press release/ article 

Ref: AstraZeneca | Image: AstraZeneca


Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions