Logo

Vifor and Angion's ANG-3777 Fail to Meet its Primary and Secondary Endpoint for Patients with High-Risk Kidney Transplant

Share this

Vifor and Angion's ANG-3777 Fail to Meet its Primary and Secondary Endpoint for Patients with High-Risk Kidney Transplant

Shots:

  • The P-III trial evaluates ANG-3777 (qd for 3days) vs PBO in a ratio (1:1) in 253 patients with kidney transplants who were at risk for developing DGF
  • The trial failed to show a significant difference from PBO on the 1EPs of eGFR @12mos. The therapy demonstrated an inconsistent benefit on 2EPs. while overall safety profile was consistent with the overall experience in its clinical development program & consistent with the published literature in a patient population
  • The results are not expected to support an indication in the studied DGF population. Additionally- the P-II exploratory trial of ANG-3777 for acute kidney injury associated with CSA-AKI is ongoing & results are expected in Q4’21

 ­ | Ref: Globe Newswire | Image: Businesswire

Click here to­ read the full press release 

Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions