Samsung Bioepis Presents Five-year Follow-up Results of Ontruzant (biosimilar- trastuzumab) in Early or Locally Advanced HER2 Positive Breast Cancer at ESMO 2021
Shots:
- The P-III study evaluates the cardiac safety profiles & efficacy of Ontruzant vs reference trastuzumab in 367 patients with HER2 positive early or LA BC for 4yrs. after randomization
- Patients were randomized to receive 8 cycles of either Ontruzant or TRZ with concurrent neoadjuvant CT. After surgery- patients received 10 cycles of biosimilar trastuzumab or TRZ completing 1yrs. of treatment
- In follow up study- the reduction in asymptomatic LVEF at both groups- 3 patients recovering with LVEF ≥ 50%- no cases of heart failure or cardiac death observed- EFS rates (82.8% vs 79.7%)- OS rates (93.1% vs 86.7%)- number of events i.e. recurrence- progression- or death (17.2% vs 21%)
| Ref: Globe Newswire | Image: Samsung Bioepis
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Tuba was Senior Editor at PharmaShots. She was curious, creative, and passionate about recent updates and innovations in the life sciences industry. She covered Biopharma, MedTech, and Digital health segments. Tuba also had an experience in digital and social media marketing and ran the campaigns independently. She can be contacted at [email protected]
